Table 1. Plasma characteristics of Reversa mice after 5 weeks of α-miR control or α-miR33 treatment.
Normoglycemic | Diabetic | ||||
---|---|---|---|---|---|
| |||||
mg/dL | Baseline | Con α-miR | α-miR33 | Con α-miR | α-miR33 |
Glucose | - | 113±10 | 116±6 | 410±35*** | 365±29*** |
TC | 863±46 | 101±14 | 93±10 | 83±13 | 94±9 |
HDL-C | 35±3 | 25±3 | 33±3# | 35±2 | 50±6* |
TG | - | 30±6 | 31±5 | 52±5# | 64±11# |
All data are expressed as mean ± SEM (n>10).
p≤0.05 vs. con α-miR normoglycemic;
p≤0.05,
p≤0.001 vs. con α-miR diabetic.