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. Author manuscript; available in PMC: 2015 Oct 21.
Published in final edited form as: Vaccine. 2014 Sep 20;32(46):6039–6048. doi: 10.1016/j.vaccine.2014.09.021

Figure 6. Activated CD8+ T cells directly induced apoptosis of MDSCs.

Figure 6

Purified splenic CD11b+ Ly6GHi MDSCs incubated with E7-specific T cells, OT-1 T cells or medium control for up to 24 hours. A. Representative flow cytometry histograms depicting the frequency of CD11b+ Ly6GHi Annexin V+ MDSC co-cultured with E7-specific T cells. B. Bar graph quantification of the data A (mean ± S.E.). C. Representative flow cytometry histograms depicting the frequency of CD11b+ Ly6GHi Annexin V+ MDSCs co-cultured with OT-1 T cells. D. Bar graph quantification of the data C (mean ± S.E.).