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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Environ Int. 2014 Aug 10;73:135–142. doi: 10.1016/j.envint.2014.06.020

Table 2.

Adjusted Mean Shifts in Age at Pubertal Onset (Months, 95% CIs) by Quartiles of Wet-Weight Serum OCP Concentrations Among 350 Russian Boys

G2+ (n=346)a TV > 3 mL (n=346)b P2+ (n=344)c
Mean Shift (months) and 95% CI p-value Mean Shift (months) and 95% CI p-value Mean Shift (months) and 95% CI p-value
HCBd
 Q1 REF REF REF
 Q2 −0.68 (−7.45, 6.08) 0.84 3.56 (−2.57, 9.70) 0.25 −0.08 (−5.77, 5.60) 0.82
 Q3 6.11 (−0.66, 12.88) 0.08 7.87 (1.73, 14.02) 0.01 4.65 (−1.04, 10.34) 0.11
 Q4 −2.72 (−9.55, 4.10) 0.43 4.73 (−1.42, 10.88) 0.13 4.59 (−1.13, 10.31) 0.12
p for trend 0.93 0.06 0.04
β-HCHe
 Q1 REF REF REF
 Q2 2.64 (−4.20, 9.47) 0.45 −0.05 (−6.29, 6.19) 0.99 −1.69 (−7.47, 4.09) 0.57
 Q3 1.91 (−4.88, 8.69) 0.58 1.79 (−4.38, 7.96) 0.57 3.43 (−2.33, 9.19) 0.24
 Q4 4.07 (−2.78, 10.92) 0.24 1.35 (−4.91, 7.62) 0.67 −1.33 (−7.18, 4.51) 0.65
p for trend 0.30 0.56 0.91
p,p′-DDEf
 Q1 REF REF REF
 Q2 −0.08 (−6.82, 6.66) 0.98 −0.19 (−6.32, 5.95) 0.95 3.85 (−1.88, 9.58) 0.19
 Q3 −0.20 (−6.96, 6.55) 0.95 −0.44 (−6.61, 5.73) 0.89 3.99 (−1.74, 9.72) 0.17
 Q4 4.89 (−2.05, 11.83) 0.17 3.31 (−3.05, 9.66) 0.31 3.33 (−2.55, 9.21) 0.27
p for trend 0.20 0.36 0.28
a

G2+ model adjusted for baseline covariates: boys’ total serum lipids, birth weight, macronutrients (total caloric intake, percent calories from dietary carbohydrates, fat, and protein), blood lead levels; missing birth weight (n=1), macronutrients (n=3)

b

TV > 3 mL model adjusted for baseline covariates: boys’ total serum lipids, birth weight, macronutrients (total caloric intake, percent calories from dietary carbohydrates, fat, and protein), blood lead levels; missing birth weight (n=1), macronutrients (n=3)

c

P2+ model adjusted for baseline covariates: boys’ total serum lipids, macronutrients (total caloric intake, percent calories from dietary carbohydrates, fat, and protein), blood lead levels, maternal age at birth, household income; missing macronutrients (n=3), household income (n=1), maternal age at birth (n=2)

d

HCB wet-weight quartiles (Q1–Q4, pg/g serum): Q1: 169–516; Q2: 517–751; Q3: 752–1,156; Q4: 1,157–15,482

e

β-HCH wet-weight quartiles (Q1–Q4, pg/g serum): Q1: 209–567; Q2: 568–814; Q3:815–1,294 Q4: 1,295–13,732

f

p,p′-DDE wet-weight quartiles (Q1–Q4, pg/g serum): Q1: 261–907; Q2: 908–1,406; Q3: 1,407–2,327; Q4: 2,328–41,301