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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Environ Int. 2014 Aug 10;73:135–142. doi: 10.1016/j.envint.2014.06.020

Table 3.

Adjusted Mean Shifts in Age at Pubertal Onset (Months, 95% CIs) by Quartiles of Wet-Weight Serum OCPs Additionally Adjusted for Baseline BMI Categories and Height Z-scores in 350 Russian Boys

G2+ (n=346)a TV > 3 mL (n=346)b P2+ (n=344)c
Mean Shift (months) and 95% CI p-value Mean Shift (months) and 95% CI p-value Mean Shift (months) and 95% CI p-value
HCBd
 Q1 REF REF REF
 Q2 −0.40 (−6.77, 5.98) 0.90 3.66 (−2.28, 9.60) 0.23 −0.30 (−5.89, 5.30) 0.92
 Q3 4.38 (−2.24, 11.00) 0.19 6.65 (0.46, 12.83) 0.04 2.95 (−2.86, 8.76) 0.21
 Q4 −4.34 (−10.98, 2.29) 0.20 3.42 (−2.74, 9.58) 0.28 2.82 (−3.03, 8.67) 0.34
p for trend 0.54 0.21 0.23
β-HCHe
 Q1 REF REF REF
 Q2 4.04 (−2.50, 10.59) 0.23 0.20 (−5.92, 6.33) 0.95 −2.01 (−7.76, 3.73) 0.49
 Q3 0.42 (−6.39, 7.23) 0.90 −0.33 (−6.71, 6.05) 0.92 0.94 (−5.09, 6.97) 0.76
 Q4 2.06 (−4.77, 8.96) 0.55 −1.24 (−7.71, 5.23) 0.71 −4.74 (−10.93, 1.45) 0.13
p for trend 0.78 0.69 0.24
p,p′-DDEf
 Q1 REF REF REF
 Q2 0.84 (−5.96, 7.64) 0.81 −0.68 (−6.99, 5.63) 0.83 2.85 (−3.06, 8.76) 0.34
 Q3 −0.08 (−6.83, 6.66) 0.98 −1.68 (−7.99, 4.62) 0.60 3.08 (−2.80, 8.97) 0.30
 Q4 1.29 (−5.86, 8.43) 0.72 0.60 (−7.30, 6.10) 0.86 0.10 (−6.11, 6.31) 0.97
p for trend 0.81 0.79 0.98
a

G2+ model adjusted for baseline covariates: boys’ total serum lipids, birth weight, macronutrients (total caloric intake, percent calories from dietary carbohydrates, fat, and protein), blood lead levels, WHO BMI z-score, WHO height z-score; missing birth weight (n=1), macronutrients (n=3)

b

TV > 3 mL model adjusted for baseline covariates: boys’ total serum lipids, birth weight, macronutrients (total caloric intake, percent calories from dietary carbohydrates, fat, and protein), blood lead levels, WHO BMI z-score, WHO height z-score; missing birth weight (n=1), macronutrients (n=3)

c

P2+ model adjusted for baseline covariates: boys’ total serum lipids, macronutrients (total caloric intake, percent calories from dietary carbohydrates, fat, and protein), blood lead levels, maternal age at birth, household income, WHO BMI z-score, WHO height z-score; missing macronutrients (n=3), household income (n=1), maternal age at birth (n=2)

d

HCB wet-weight quartiles (Q1–Q4, pg/g serum): Q1: 169–516; Q2: 517–751; Q3: 752–1,156; Q4: 1,157–15,482

e

β-HCH wet-weight quartiles (Q1–Q4, pg/g serum): Q1: 209–567; Q2: 568–814; Q3:815–1,294 Q4: 1,295–13,732

f

p,p′-DDE wet-weight quartiles (Q1–Q4, pg/g serum): Q1: 261–907; Q2: 908–1,406; Q3: 1,407–2,327; Q4: 2,328–41,301