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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: J Thromb Haemost. 2014 Sep 30;12(10):1706–1716. doi: 10.1111/jth.12657

Figure 1. PAI-2 deficiency enhances thrombus resolution and decreases PAI-1 levels.

Figure 1

(A) Thrombus weight normalized to mouse body weight over time in PAI-2 -/- mice compared to WT (Day 12 p<0.005; n=13-16, Day 2 n=9-12, Day 4 n=17, Day 8 n=7-10). (B) Thrombus weight over time in PAI-2 -/- mice compared to WT (Day 12 p<0.005; n=13-16, Day 2 n=9-12, Day 4 n=17, Day 8 n=7-10). (C) Assay of total PAI-1 in WT and PAI-2 -/- thrombus protein lysates by ELISA (Day 2 p=0.019, Day 4 p=0.041, Day 12 p<0.005; n=3). (D) Assay of total PAI-2 in WT and PAI-1 -/- thrombus protein lysates by ELISA (n=3).