Skip to main content
. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: J Thromb Haemost. 2014 Sep 30;12(10):1706–1716. doi: 10.1111/jth.12657

Figure 2. PAI-1 deficiency impairs thrombus formation and enhances thrombus resolution.

Figure 2

(A) Thrombus weight normalized to mouse body weight over time in PAI-1 -/- mice compared to WT (Day 2 p=0.045 n=8-12, Day 4 p=0.049 n=11-17, Day 8 p<.005 n=3-7, Day 12 p<0.005; n=10-13). (B) Thrombus weight over time in PAI-1 -/- mice compared to WT (Day 2 p=0.046 n=8-12, Day 4 p=0.018 n=11-17, Day 8 p=0.065 n=3-7, Day 12 p<0.005; n=10-13). (C) Percent of thrombus remaining on day 12 in PAI-2 -/- (p=0.012), and PAI-1 -/- (p=0.007) compared to WT mice, as assessed by thrombus weight at day 12 divided by thrombus weight on day 2.