Fig. 5.
T-dCyd and aza-T-dCyd are effective at slowing growth of NCI-H23 lung tumors implanted in nude mice, a Mice were treated i.p. with vehicle (saline) or T-dCyd at 1.3 and 0.9 mg/kg/dose three times a day, 4 h apart, daily for 9 days, b Mice were treated i.p. with vehicle (saline) (qld × 5, qlw × 5), 1 mg/kg/dose aza-dCyd (qld × 5, qlw × 3) or 5 mg/kg/dose T-dCyd (qld × 5, qlw × 5). c Aza-T-dCyd is effective at slowing growth of NCI-H23 lung tumors implanted in nude mice. Mice were treated i.p. with vehicle (saline) or aza-T-dCyd at 10 and 6.7 mg/kg/dose daily for 9 days (qld × 9)