Appendix Table 4e.

Likelihood ratio tests for smoking during pregnancy and general cognitive functioning

Model name	Number of estimated parameters	−2 log likelihood	P-value; test again previous model with more estimated parameters
ACMPE – ACMPE	38	1154273.6	NA
ACPE – ACPE	36	1154275.8	0.327
ACE – ACE	34	1154278.3	0.289
AE – AE	32	1154790.9	<0.001
CE – CE	32	1154927.5	<0.001
ACE – AE	33	1154339.4	<0.001
ACE – CE	33	1154626.1	<0.001
ACE – AC	33	1154321.9	<0.001

Abbreviations: NA, not applicable.

Note: “Best-fitting model” marked in bold letters. Each model is tested against previous model with more estimated parameters. The model name implies which parameters that are included, it is stated as ACMPE – ACMPE, where the first five letters tells us which of the variance parameters in general cognitive functioning that are included (i.e., $a_o^2,c_o^2,m_o^2,p_o^2$, and $e_o^2$), and the five last letters tells us which of the cross-phenotype parameters that are included (i.e., r_A, r_C, r_M, r_P, and r_E). All of the variance parameters in maternal smoking during pregnancy are included in all models.