. Author manuscript; available in PMC: 2015 Nov 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2014 Jul 10;20(11):1861–1864. doi: 10.1016/j.bbmt.2014.06.039

Table 2.

Biomarker medians (25^th, 75^th percentile) by group over time^*

	Day +7				Day +14				Day +21				Day +30
	aGVHD⁺	No aGVHD	C- stat	p- value	aGVHD⁺	No aGVHD	C- stat	p- value	aGVHD⁺	No aGVHD	C- stat	p- value	aGVHD⁺	No aGVHD	C- stat	p- value
ST2 ng/ml	73.2 (25.9, 149.2)	25.7 (12.9, 42.7)	0.72	0.03	53.8 (26.8, 95.9)	19.8 (14.4, 42.3)	0.74	0.02	28.3 (18.8, 143.9)	16.2 (12.5, 23.7)	0.75	0.02	26.3 (10.3, 134.4)	15.0 (11.2, 22.0)	0.68	0.09
Reg3α pg/ml	51.4 (24.2, 93.5)	40.5 (20.0, 53.2)	0.63	0.20	194.8 (46.7, 825.0)	50.3 (23.6, 72.9)	0.73	0.03	178.1 (54.0, 649.5)	41.7 (29.6, 64.6)	0.76	0.01	130.6 (52.5, 605.2)	51.4 (30.1, 87.8)	0.73	0.03
Elafin pg/ml	7628.3 (4303.0, 18557.2)	5088.0 (3530.3, 8057.8)	0.62	0.26	10156.8 (5531.0, 14428.2)	4610.0 (3416.2, 8140.6)	0.71	0.04	7793.0 (4610.0, 10586.5)	5931.4 (3916.6, 10941.0)	0.54	0.74	6987.6 (5355.0, 12224.5)	8794.1 (5786.9, 15783.8)	0.57	0.45
TNFR1 pg/ml	4348.9 (2408.7, 6562.1)	3747.1 (2025.1, 4341.2)	0.62	0.23	5695.1 (2946.4, 9701.1)	3809.8 (2391.9, 4935.8)	0.64	0.20	5443.2 (3974.0, 6784.1)	4528.0 (2692.6, 5492.5)	0.67	0.11	4421.9 (3261.4, 7989.6)	4094.6 (3150.5, 5572.2)	0.49	0.33
sIL2Rα (pg/ml	883.2 (254.6, 1673.0)	137.5 (50.1, 481.0)	0.70	0.14	269.1 (26.1, 3051.3)	95.7 (83.8, 265.3)	0.61	0.41	930.5 (194.3, 2098.1)	216.6 (167.4, 398.1)	0.68	0.13

For ST2, Reg3α, Elafin, and TNFR1, sample sizes were 17, 16, 17, and 16 for GVHD+ and 17, 15, 15, and 16 for GVHD- for Day +7, +14, +21, and +30 respectively. For sIL2Rα, sample sizes were 12, 10, and 10 for GVHD+ and 10, 13, and 14 for GVHD- for Day +7, +14, and +21 respectively.