Table 2.

Comparison of observed prostate cancer incidence rates to average prostate cancer risks based on bmiPCPTRC

	(A) Total prostate cancer (PCa)					(B) Gleason grade ≥7 prostate cancer (HGPCa)
Subgroup	N	Obs. PCa n (%)	Ave. Risk (%)	AUC	P Valuea	Nd	Obs. HGPCa n (%)	Ave. Risk (%)	AUC	P Valuea
All	3258	1902 (58.4)	40.4	0.713		2869	525 (18.3)	13.3	0.705
PSA <4.0 ng/mL	1459	651 (44.6)	33.4	0.748	<0.001	1335	143 (10.7)	7.8	0.708	0.01
PSA ≥4.0 ng/mL	1799	1251 (69.5)	46.1	0.598		1534	382 (24.9)	18.0	0.642
Normal DRE	2442	1411 (57.8)	37.6	0.711	0.15	2139	381 (17.8)	12.1	0.700	0.58
Abnormal DRE	816	491 (60.2)	48.8	0.741		730	144 (19.7)	16.6	0.714
Age: ≥ 65 yrs	1819	1074 (59.0)	41.1	0.725	0.15	1598	333 (20.8)	14.7	0.696	0.75
Age: < 65 yrs	1439	828 (57.5)	39.6	0.698		1271	192 (15.1)	11.5	0.703
No Family History	804	528 (65.7)	45.1	0.730	0.21	694	127 (18.3)	12.8	0.682	0.26
Family History	2454	1374 (56.0)	38.9	0.702		2175	398 (18.3)	13.4	0.712
BMI<25	702	364 (51.9)	38.2	0.697	0.56	632	89 (14.1)	11.9	0.694	0.28
25≤BMI<30	1600	954 (59.6)	40.2	0.711	0.53	1399	249 (17.8)	12.7	0.729	0.008
BMI≥30	956	584 (61.1)	42.6	0.724	0.30b	838	187 (22.3)	15.2	0.658	0.29b
White	2643	1510 (57.1)	40.6	0.718	0.86	2359	422 (17.9)	11.7	0.716	0.32
AA	453	286 (63.1)	40.1	0.713	0.38	388	82 (21.1)	23.2	0.684	0.37
Hispanic (non-AA)	106	71 (67.0)	38.8	0.655	0.31c	71	11 (15.5)	11.4	0.605	0.19c

AA=African American

^aDifference in AUC between two independent subgroups (current row vs. the row below it) using a Z statistic

^bDifference in AUC between BMI>30 and BMI<25

^cDifference in AUC between Hispanic and White

^d389 men were excluded due to missing Gleason score