Table 1.
Groups | Pretreatment dose | Test day dose |
---|---|---|
Acute control group | Saline | 0.25 mg/kg NPA |
Sensitization group | 0.5 mg/kg NPA | 0.25 mg/kg NPA |
Sensitization group | 1 mg/kg NPA | 0.25 mg/kg NPA |
Sensitization group | 2 mg/kg NPA | 0.25 mg/kg NPA |
Acute control group | Saline | 0.5 mg/kg NPA |
Sensitization group | 1 mg/kg NPA | 0.5 mg/kg NPA |
Sensitization group | 2 mg/kg NPA | 0.5 mg/kg NPA |
Acute control group | Saline | 1 mg/kg NPA |
Sensitization group | 2 mg/kg NPA | 1 mg/kg NPA |
Note: Rats were pretreated on PD 12, PD 16, PD 20, or PD 24 and tested 24 h later.