Figure 3. Effects of treatment with either aspirin (ASA) or clopidogrel on the accelerated thrombus development in arterioles induced by transient (5 min) ischemia and 24 hrs reperfusion.
The following numbers of mice were included in each group: Controls (n=13), MCAo/R (n=8), MCAo/R + ASA (1d) (n=7), (6d) (n=6), MCAo/R + clopidogrel (1d) (n=5). Onset indicates the time of onset of platelet deposition on the vessel wall, while cessation refers to the time required for complete flow cessation. *denotes p<0.05 compared to control (day-0) response.