Table 3. Ocular symptom score before and after treatment with cyclosporine A 0.05% (Restasis) twice per day for 3 months.
First visit | After 1 month | After 3 months | |
---|---|---|---|
Ocular fatigue | |||
Average | 3.07±0.92 | 1.21±0.95 | 0.57±0.64 |
P-value | 0.01* | 0.01* | |
Discharge | |||
Average | 2.92±0.92 | 1.85±0.87 | 1.50±0.65 |
P-value | 0.06 | 0.02* | |
Foreign body sensation | |||
Average | 3.35±0.63 | 1.50±0.65 | 0.71±0.72 |
P-value | 0.01* | 0.01* | |
Dryness | |||
Average | 2.64±1.15 | 1.35±0.74 | 0.5±0.65 |
P-value | 0.01* | 0.01* | |
Discomfort | |||
Average | 2.92±0.92 | 2.21±0.80 | 1.07±0.61 |
P-value | 0.08 | 0.01* | |
Sticky sensation | |||
Average | 1.85±1.16 | 2.21±1.05 | 1.5±0.94 |
P-value | 0.194 | 0.021* | |
Pain | |||
Average | 2.78±0.80 | 1.78±0.89 | 1.21±1.19 |
P-value | 0.080 | 0.04* | |
Tearing | |||
Average | 2.57±0.93 | 2.50±0.52 | 2.28±1.13 |
P-value | 0.705 | 0.018* | |
Itching sensation | |||
Average | 3.42±0.85 | 2.07±1.21 | 1.92±1.27 |
P-value | 0.080 | 0.04* | |
Burning sensation | |||
Average | 2.35±1.28 | 1.92±1.14 | 1.35±1.08 |
P-value | 0.279 | 0.009* | |
Heavy sensation | |||
Average | 2.78±0.69 | 2.36±0.74 | 2.36±0.74 |
P-value | 0.058 | 0.013* | |
Excessive blinking | |||
Average | 1.50±1.22 | 1.57±1.22 | 1.21±1.05 |
P-value | 0.703 | 0.409 | |
Uncomfortable in windy conditions | |||
Average | 2.71±0.91 | 2.00±0.55 | 1.35±0.92 |
P-value | 0.01* | 0.001* | |
Uncomfortable in very dry conditions | |||
Average | 2.92±0.91 | 2.14±0.86 | 1.42±1.01 |
P-value | 0.026* | 0.001* |
Data were analyzed using the Wilcoxon signed-rank test (*P<0.05 is considered statistically significant).