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. 2014 Aug 1;28(10):1212–1217. doi: 10.1038/eye.2014.174

Table 3. Ocular symptom score before and after treatment with cyclosporine A 0.05% (Restasis) twice per day for 3 months.

  First visit After 1 month After 3 months
Ocular fatigue
 Average 3.07±0.92 1.21±0.95 0.57±0.64
P-value   0.01* 0.01*
       
Discharge
 Average 2.92±0.92 1.85±0.87 1.50±0.65
P-value   0.06 0.02*
       
Foreign body sensation
 Average 3.35±0.63 1.50±0.65 0.71±0.72
P-value   0.01* 0.01*
       
Dryness
 Average 2.64±1.15 1.35±0.74 0.5±0.65
P-value   0.01* 0.01*
       
Discomfort
 Average 2.92±0.92 2.21±0.80 1.07±0.61
P-value   0.08 0.01*
       
Sticky sensation
 Average 1.85±1.16 2.21±1.05 1.5±0.94
P-value   0.194 0.021*
       
Pain
 Average 2.78±0.80 1.78±0.89 1.21±1.19
P-value   0.080 0.04*
       
Tearing
 Average 2.57±0.93 2.50±0.52 2.28±1.13
P-value   0.705 0.018*
       
Itching sensation
 Average 3.42±0.85 2.07±1.21 1.92±1.27
P-value   0.080 0.04*
       
Burning sensation
 Average 2.35±1.28 1.92±1.14 1.35±1.08
P-value   0.279 0.009*
       
Heavy sensation
 Average 2.78±0.69 2.36±0.74 2.36±0.74
P-value   0.058 0.013*
       
Excessive blinking
 Average 1.50±1.22 1.57±1.22 1.21±1.05
P-value   0.703 0.409
       
Uncomfortable in windy conditions
 Average 2.71±0.91 2.00±0.55 1.35±0.92
P-value   0.01* 0.001*
       
Uncomfortable in very dry conditions
 Average 2.92±0.91 2.14±0.86 1.42±1.01
P-value   0.026* 0.001*

Data were analyzed using the Wilcoxon signed-rank test (*P<0.05 is considered statistically significant).