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. 2014 Oct 3;15(1):848. doi: 10.1186/1471-2164-15-848

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© Russell et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Comparative analysis of overrepresentation of homopolymeric tracts as a function of nucleotide content. (A) The slope of overrepresentation (slope_R) of each homopolymer tract (see key in B) plotted as a function of the fraction of each nucleotide content (Fraction_i) in upstream and downstream proximal flanking regions. Only poly dC tracts in upstream proximal flanking regions show a significant correlation as indicated. (B) The threshold of homopolymer tract_i plotted as a function of Fraction_i in upstream and downstream proximal flanking regions. All linear regression analyses (dotted lines) were significant, with the coefficient of correlation (r ²) reported in the key.