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Weekly mean scores as measured by VAS. At baseline, each group was well matched for severity of their VAS scores. After injections, The VAS scores of 25U and 75U groups reduced significantly compared to placebo as early as week 1, and sustained until week 8 throughout the study (*P < 0.017, **P < 0.017) . There was no significant difference between 25U and 75U groups throughout the study (P > 0.05).
