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. 2004 Apr 28;32(8):2386–2395. doi: 10.1093/nar/gkh562

Figure 1.

Figure 1

Circular representation of the three sequenced Listeria genomes. Each concentric circle represents genomic data and is numbered from the outermost to the innermost circle. The outermost circle indicates the AscI (black), NotI (red), SfiI (blue) and SrfI (green) restriction map of the closed L.monocytogenes serotype 4b F2365 strain. The second and third circles represent the predicted strain F2365 ORFs on the + and – strands, respectively, colored by role categories: salmon, amino acid biosynthesis; light blue, biosynthesis of cofactors, prosthetic groups and carriers; light green, cell envelope; red, cellular processes; brown, central intermediary metabolism; yellow, DNA metabolism; green, energy metabolism; purple, fatty acid and phospholipid metabolism; pink, protein fate/synthesis; orange, purines, pyrimidines, nucleosides and nucleotides; blue, regulatory functions; gray, transcription; teal, transport and binding proteins; black, hypothetical and conserved hypothetical proteins. The fourth circle shows the GC-skew. The fifth (strain F2365), seventh (strain H7858) and ninth (F6854) circles indicate ORFs involved in virulence: ORFs other than internalins (red), internalins (blue), putative prophage or monocin regions (dark green), transposable elements (gold), CRISPR elements (light blue), strain-specific genes (half-sized light gray ticks) and contig breakpoints (quarter-sized black ticks) relative to the closed F2365 strain. The sixth circle represents the number of SNPs per 5 kb for the H7858 strain, relative to the F2365 strains: blank, no SNPs (or unsequenced region); quarter-sized gold ticks, 1–30 SNPs; half-sized red ticks, 31–50 SNPs; three quarter-sized dark green ticks, 51–80 SNPs; full-sized blue ticks, more than 81 SNPs. The eighth circle represents the number of SNPs per 5 kb for the F6854 strain, relative to the F2365 strain: blank, no SNPs (or unsequenced region); quarter-sized gold ticks, 1–75 SNPs; half-sized red ticks, 76–200 SNPs; three quarter-sized dark green ticks, 201–300 SNPs; full-sized blue ticks, more than 301 SNPs. The tenth circle denotes atypical regions (χ2 value). The eleventh circle depicts tRNA (green), rRNA (blue) and sRNA (red) for the F2365 strain.