. 2014 Oct 14;20(38):13692–13704. doi: 10.3748/wjg.v20.i38.13692

Table 3.

Summary of recently published meta-analysis examining laparoscopic distal gastrectomy vs open distal gastrectomy for gastric cancer

Ref.	Trials included (n)	Laparoscopic/open procedures (n)	TumOR = characteristics	Operative time (min) (WMD)	Blood loss (mL) (WMD)	Harvested lymph nodes (WMD)	Length-of-stay (WMD)	Complication rates	Mortality
Memon et al[62], 2008	4 RCT’s	82/80	EGC, GC	+83 (P < 0.001)	-104 (P = 0.02)	-4.3 (P < 0.001)	-3.3 d (P = 0.14)	OR = 0.66 (P = 0.14)	OR = 0.94 (P = 0.94)
Chen et al[60], 2009	6 RCT’s	323/306	EGC	+87 (P < 0.001)	-108 (P = 0.001)	-4.9 (P < 0.001)	-2.0 d (P = 0.14)	RR = 0.61 (P = 0.01)	Risk difference 0.01 (P = 0.32)
Kodera et al[61], 2010	6 RCT’s	343/323	EGC, GC	+82 (P < 0.001)	-118 (P < 0.001)	-4.8 (P < 0.001)	NA	OR = 0.46 (P = 0.003)	OR = 0.17 (P = 0.86)
Ohtani et al[63], 2011	5 RCT’s	164/162	EGC, GC	+82 (P < 0.001)	-122 (P < 0.001)	-4.8 (P < 0.001)	-2.5 d (P = 0.04)	OR = 0.38 (P = 0.01)	OR = 0.47 (P = 0.54)
Viñuela et al[59], 2012	6 RCT’s	1658/1397	ECG, GC	+48.3 (P < 0.001)	-118 (P < 0.001)	-3.9 (P < 0.001)	-3.6 (P < 0.001)	OR = 0.59 (P < 0.001)	OR = 0.64 (P = 0.39)
Viñuela et al[59], 2012	19 NRCT’s	1658/1397	ECG, GC	+48.3 (P < 0.001)	-118 (P < 0.001)	-3.9 (P < 0.001)	-3.6 (P < 0.001)	OR = 0.59 (P < 0.001)	OR = 0.64 (P = 0.39)

RCT: Randomized controlled trial; NRCT: Non-randomized controlled trial; EGC: Early gastric cancer; GC: Gastric cancer (all stages); WMD: Weighted mean difference; NA: Not available.