Table 5.

Prospective phase 2 trials of preoperative chemo-radiotherapy

Ref.	Year	No. of patients	Induction CT	CRT	Proceeded to surgery	R0 resection	pCR
Ajani et al[62]	2004	34	x2 FU/Cis/LV	45Gy/FU	85%	70%	30%
Ajani et al[63]	2005	41	x2 FU/Cis/Paclitaxel	45Gy/FU/Paclitaxel	98%	78%	20%
Ajani et al[64]	2006	49	x2 FU/Cis/LV	45Gy/FU/Paclitaxel	83%	77%	26%

pCR: Pathological complete response; Cis: Cisplatin; CRT: Chemo-radiotherapy; FU: Fluorouracil; CT: Chemotherapy; LV: Leucovorin.