Table 7.

Clinical trials of cetuximab and panitumumab

Patients	Phase	Treatment	n	OS (m)	PFS (m)	RR	DCR
Previously untreated advanced gastric cancer (EXPAND)	III	Capecitabine + cisplatin	449	10.7	5.6	29%	71%
		Capecitabine + cisplatin + cetuximab	455	9.4	4.4	30%	73%
Untreated metastatic or locally advanced oesophagogastric adenocarcinoma (REAL 3)	III	EOC (epirubicin + oxaliplatin + capecitabine)	275	11.3	6.0	42%	63%
		Modified dose EOC + panitumumab	278	8.8	7.4	46%	64%

DCR: Disease control rate; N/A: Not available; OS: Overall survival; PFS: Progression-free-survival; RR: Response rate.