Table 1.
Types and subtypes | Main localization | Sex | Frequency | Microscopic findings |
Immunophenotype |
Association with PDAC | ||||
MUC1 | MUC2 | MUC5AC | MUC6 | CDX2 | ||||||
Main-duct type IPMN | ||||||||||
Intestinal type | Pancreatic head | M(>)F | 36% | Papillae lined by columnar cells | - | + | + | - | + | 34% |
Pancreatobiliary type | Pancreatic head | M(>)F | 7% | Papillae lined by cuboidal cells | + | - | + | + | - | 58% |
Oncocytic type | Pancreatic head | M(>)F | 9% | Complexe papillae lined by multiple layer of cells with eosinophilic cytoplasma | + | - | + | + | - | 25% |
Branch-duct type IPMN | ||||||||||
Gastric type | Uncinate process | M(>)F | 49% | Gastric foveolar epithelium | - | - | + | - | - | 6% |
IPMN: Intraductal papillary mucinous neoplasm; PDAC: Pancreatic ductal adenocarcinoma.