Table 2.
Liver stiffness cut-off values for the diagnosis of significant (≥ F2) and advanced (≥ F3) fibrosis and cirrhosis (F4) (n = 70)
| Value | ≥ F2 | ≥ F3 | = F4 |
| Number of patients, n (%) | 55 (78.6) | 35 (50.0) | 22 (31.4) |
| Optimal cut-off1 (kPa) | 8.60 | 10.46 | 14.00 |
| Sensitivity (%) | 78.20 | 88.60 | 77.30 |
| Specificity (%) | 93.30 | 80.00 | 85.40 |
| Negative likelihood ratio | 11.73 | 4.43 | 5.30 |
| Positive likelihood ratio | 0.23 | 0.14 | 0.27 |
1
Cut-off value was calculated to maximize the sum of sensitivity and specificity. kPa: Kilopascals.