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. Author manuscript; available in PMC: 2014 Oct 13.
Published in final edited form as: Neurodegener Dis. 2013 Sep 5;13(1):24–28. doi: 10.1159/000351097

Fig. 1. Survival curves of time to onset of dyskinesia according to COMT (a), MAO-A (b) or BDNF (c) genotype.

Fig. 1

Kaplan-Meier curves demonstrating duration from PD onset to first reported incidence of LID in patients stratified according to genotype. For the BDNF Val66Met polymorphism, given the low prevalence of the variant Met allele in European populations, Met/Met homozygous patients were pooled with Val/Met heterozygotes for statistical analysis. As the MAO-A gene is X-linked, males and females were analysed both separately and with male hemizygotes pooled with female homozygotes to directly compare the effects of T or G allele carriage.