Table 4.
TNF-α (A), IL-4 (B) and IL-5 (C) concentrations in BAL fluid recovered from male Balb/c mice following drug treatment. Cytokine concentrations were measured using a Biolplex ELISA system. Each study group contained n = 8 mice.
| Concentration in BAL fluid (pg/ml) | |||
| Study Group | TNFα | IL-4 | IL-5 |
| A | 19.9 ± 5.3 | 10.7 ± 0.5 | 18.2 ± 0.58 |
| B | 43.2 ± 5.1 a | 123.6 ± 66.3 a | 1077.1 ± 273.5 a |
| C | 41.6 ± 3.6 | 120.3 ± 5.3 | 1339.7 ± 120.5 |
| D | 22.9 ± 4.6 c | 50.7 ± 2.4 c | 591.9 ± 108.2 c |
| E | 47.1 ± 5.0 | 129.4 ± 11.0 | 1652.9 ± 174.1 |
| F | 41.6 ± 6.8 | 112.8 ± 11.9 | 1592.5 ± 301.4 |
| G | 46.5 ± 6.5 | 139.3 ± 40.7 | 1290.3 ± 218.4 |
| H | 38.3 ± 7.2 | 110.1 ± 18.0 | 1007.6 ± 194.5 |
| I | 39.1 ± 7.6 | 104.8 ± 27.5 | 1634.9 ± 367.7 |
| J | 16.7 ± 3.6 c | 15.8 ± 2.1 b | 227.9 ± 45.0 b |
a p < 0.001 compared to non OVA challenged mice (Group A), b p < 0.01 compared to OVA challenged mice orally gavaged with saline (Group B), c p < 0.05 compared to OVA challenged mice orally gavaged with saline (Group B)