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. Author manuscript; available in PMC: 2014 Oct 13.
Published in final edited form as: J Invest Dermatol. 2014 Mar 28;134(9):2458–2468. doi: 10.1038/jid.2014.162

Figure 1. Accelerated wound healing in mice treated with combination of low-dose Tacrolimus and AMD3100.

Figure 1

(a) The model: on day 0, four circular excisional wounds were created in C57BL/6 or CD133+/C-L mice. (b) Wound measurements. Wound areas were determined using Adobe Photoshop software. (c) Early healing. Representative photographs of wounds in mice (n = 6) showing striking differences beginning at day 5. (d) Quantitative analysis of wound closure in mice (n = 6). * p< 0.05. (e) H&E microphotographs of wounds at day 5. Scale bar: 200 µm. (f) The splinted wound model. (g) Macroscopic analysis of skin wound healing in the splinted mice. (h) Quantitative analysis of wound closure in the splinted mice (n = 6). * p< 0.05. All data represent means ± SEM.