Table 1. Clinical staging criteria for cirrhosis of the liver.
Stage | Common description or name of the condition | Alternate description or synonym | Supporting evidence or clues |
---|---|---|---|
1.0 | Cirrhosis | Cirrhosis: Portal (alcoholic Laennec's); post-necrotic; biliary; cardiac; posthepatic cirrhosis; toxic cirrhosis | Liver biopsy or laparoscopy or documentation by physical signs and laboratory data consistent with the diagnosis |
2.0 | Cirrhosis plus: | ||
2.1 | Ascites or peripheral edema | Abdominal paracentesis (aspiration) or shifting dullness or fluid wave, or pitting edema | |
2.2 | Portal hypertension | Portal venous pressure measurement or radiologic exam of portal system or physical signs of abdominal collaterals, splenomegaly, cirrhosis, altered consciousness or mentation, neuromuscular signs (tremor, asterixis), abdominal EEG, elevated serum ammonia, factor hepaticus. | |
3.1 | Hypersplenism | Splenomegaly, cytopenia | |
3.2 | Variceal hemorrhage or bacterial peritonitis | Endoscopy or arteriography, diagnostic peritoneal tap | |
3.3 | Coagulopathy | Coagulation defects | Physical signs of bleeding and coagulation studies consistent with this finding. |
3.4 | Hepatic encephalopathy | Hepatic coma | Altered consciousness or mentation, neuromuscular signs (tremors, asterixis), elevated serum ammonia |
3.5 | Hepatorenal syndrome | Oliguria, azotemia in patient with clinically severe liver failure | |
4.0 | Death |
NOTE: EEG = electroencephalogram.
SOURCE: Gonnella (1983), pg. 334.