Table 1.
Population characteristics and clinical data.
| Population Characteristics and Clinical Data | SSDE (n = 18) | NSSDE (n = 17) | NDE (n = 14) | P Value |
|---|---|---|---|---|
| Age | ||||
| Average age (years) | 57.33 | 59.82 | 51.43 | 0.06 |
| Range (years) | 34-69 | 38-76 | 39-77 | |
| OSDI Results | ||||
| Average score | 53.84±20.49 | 36.71±23.55 | 18.56±15.99 | SSDE vs NDE 0.0001SSDE vs NSSDE 0.052NSSDE vs NDE 0.054 |
| Range | 20.83-77.77 | 2.08-81.25 | 0-27.73 | |
| Slit Lamp Examination (Number of Patients and %) | ||||
| Eyelid malpositions | 0 (0%) | 0 (0%) | 0 | SSDE and NSSDE vs NDE>0.05 |
| Blepharitis | 13 (72.22%) | 12 (70.59%) | 3 (21.43%) | SSDE and NSSDE vs NDE0.008 |
| Lid keratinisation | 4 (22.22%) | 3 (17.65%) | 0 | SSDE and NSSDE vs NDE0.196 |
| Lacrimal meniscus irregularity | 1 (5.56%) | 1 (5.88%) | 10 (71.43%) | SSDE and NSSDE vs NDE0.005 |
| Conjunctival redness | 14 (77.78%) | 10 (58.82%) | 0 | SSDE and NSSDE vs NDE0.005 |
| Follicles ± papillae (conjunctival) | 3 (16.67%) | 2 (11.76%) | 0 | SSDE and NSSDE vs NDE0.356 |
| Tear Film Evaluation | ||||
| TMH (in mm) average | 0.13 | 0.19 | 0.28 | SSDE and NSSDE vs NDE0.0001 |
| TMH (in mm) standard deviation | 0.07 | 0.07 | 0.05 | |
| BUT (in seconds) median | 3 | 4 | 11.5 | SSDE and NSSDE vs NDE0.0001 |
| BUT (in seconds) range | 2-8 | 2-8 | 10-25 | |
| Schirmer test (in mm) median | 2.5 | 6 | 12.5 | SSDE and NSSDE vs NDE0.0001 |
| Schimer test (in mm) range | 0-10 | 2-10 | 10-32 | |
| Ocular Surface Staining Evaluation | ||||
| FOGS Average | 2.22 | 1.47 | 0 | SSDE and NSSDE vs NDE0.0001 |
| FOGS Standard Deviation | 1.16 | 1.00 | 0 | |
| LGOGS Average | 2.5 | 1.76 | 0 | SSDE and NSSDE vs NDE0.0001 |
| LGOGS Standard Deviation | 1.09 | 1.09 | 0 | |
SSDE: Sjögren Syndrome Dry Eye, NSSDE: Non Sjögren Syndrome Dry Eye, NDE: Non Dry Eye; OSDI: Ocular Surface Disease Index; THM: Tear meniscus height; BUT: break up time; FOGS: Fluorescein Oxford Grading Scheme; LGOGS: Lissamine Green Oxford Grading Scheme.