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. 2014 Sep 10;15(10):3836–3845. doi: 10.1021/bm501166j

Figure 1.

Figure 1

In vitro recruitment of dendritic cells and macrophages by GM-CSF-loaded hydrogels. (A) mPEG–PLGA copolymer formulations are an injectable solution at 4 °C, but turn to gel after incubation at 37 °C for 5 min. (B) The release profiles of FITC-labeled GM-CSF from hydrogel formulations (15, 20, and 25 wt %; n = 3). (C) In vitro chemotaxis using a transwell migration assay. Chemotaxis of BMDCs and BMDMs in response to hydrogels encapsulating various doses of GM-CSF was determined by counting the number of BMDCs and BMDMs migrating to the lower compartment of transwell (n = 3).