Figure 3.

CATM predicts multiple modes of interaction along the Gly-zipper motif of ADCK3. Schematic representation of the five models of GAS_right homodimers generated by CATM for ADCK3-TM. The crossing point is marked by a black dot. The four positions that surround the crossing point are marked by a green parallelogram and are underlined in the sequence. The positions involved in interhelical packing at the dimer interface are highlighted: in red are the interfacial positions that belong to the extended Gly-zipper motif of ADCK3; all other interfacial positions are highlighted in yellow. The table summarizes the geometry of the five models: interhelical distance d; crossing angle θ; vertical (Z′) and axial (ω′) coordinates of the crossing point within the parallelogram of closest approach; and energy score E. For the geometric definitions, see Figure S2 (SI) and Mueller et al.³⁷