Table 1. Prediction of the Transmembrane Domain of the ADCK3 Homologs.

name	sequence	ΔGOcta	ΔGAppb	TMPREDc	Phobiusd	TMHMMe	ΔG predictorf	MemBraing	E(z)h
ADCK3	LANFGGLAVGLGFGALA	–0.28	+2.11	yes	50%	no	yes (+1.80)	possible (70%)	no
ADCK4	LANFGGLAVGLGLGVLA	–0.78	+1.91	yes	90%	40%	yes (+1.69)	yes (80%)	no

^aWimley–White octanol scale (kcal/mol).⁸¹

^bBiological hydrophobicity scale (kcal/mol).^80,82

^cTMPRED^76,77 at http://www.ch.embnet.org/software/TMPRED_form.html.

^dPhobius^78,79 at http://phobius.sbc.su.se.

^eTMHMM⁷² at http://www.cbs.dtu.dk/services/TMHMM-2.0.

^fΔG predictior⁸⁰ at http://dgpred.cbr.su.se (in paretheses the ΔG_App for the predicted TM segment, kcal/mol).

^gMemBrain^74,75 at http://www.csbio.sjtu.edu.cn/bioinf/MemBrain.

^hE(z) potential⁷³ at http://ez.degradolab.org/ez/original.