Table 2.
Neurologic Events and Baseline Characteristics, According to Patient.*
| Patient No. | Time from Randomization to End Point |
End-Point Classification |
Neuroradiology Finding† |
TIA† | Baseline Clinical Characteristics | ||||
|---|---|---|---|---|---|---|---|---|---|
| New Infarct |
Enlarged Infarct |
Age‡ | Systolic Blood Pressure |
Steady-State Hemoglobin |
Hemoglobin F§ | ||||
| mo | yr | mm Hg | g/dl | % | |||||
| Transfusion group | |||||||||
| 1 | 24 | Stroke | + | − | − | 7.9 | 107 | 6.7 | 4 |
| 2 | 35 | SCI | + | + | − | 8.5 | 85 | 9.8 | 17 |
| 3 | 36 | SCI | + | + | − | 7.5 | 101 | 10.3 | 19 |
| 4 | 36 | SCI | + | + | − | 9.3 | 107 | 7.9 | 13 |
| 5 | 39 | SCI | + | − | − | 9.1 | 92 | 7.5 | 2 |
| 6 | 36 | SCI | − | + | − | 8.3 | 107 | 7.2 | 10 |
| Observation group | |||||||||
| 7 | 6 | Stroke | + | + | − | 7.8 | 106 | 7.9 | NA |
| 8 | 19 | Stroke | + | − | − | 6.7 | 106 | 7.8 | NA |
| 9 | 30 | Stroke | + | − | − | 12.7 | 122 | 6.7 | NA |
| 10 | 36 | Stroke | + | − | − | 7.3 | 93 | 7.5 | 4 |
| 11 | 12 | Stroke | − | + | − | 6.6 | 107 | 8.0 | 9 |
| 12 | 19 | Stroke | − | − | + | 7.1 | 96 | 6.5 | 18 |
| 13 | 35 | Stroke | − | − | − | 10.3 | 100 | 6.1 | 0 |
| 14 | 16 | SCI | + | − | − | 8.0 | 110 | 7.7 | 8 |
| 15 | 27 | SCI | + | − | − | 6.3 | 103 | 8.4 | NA |
| 16 | 34 | SCI | + | − | − | 6.9 | 107 | 7.7 | 18 |
| 17 | 37 | SCI | + | − | − | 6.7 | 109 | 8.0 | 25 |
| 18 | 41 | SCI | + | − | − | 12.7 | 118 | 6.9 | 4 |
| 19 | 41 | SCI | + | − | − | 6.7 | 112 | 9.4 | 9 |
| 20 | 44 | SCI | + | − | − | 9.6 | 120 | 10.2 | 16 |
| 21 | 12 | TIA | − | − | + | 12.3 | 136 | 7.7 | 13 |
| 22 | 13 | TIA | − | − | + | 7.1 | 87 | 8.6 | 15 |
*
The baseline characteristics were determined at the time of initial screening. NA denotes not available, SCI silent cerebral infarct, and TIA transient ischemic attack.
†
A plus sign indicates that the end-point event occurred, and a minus sign that the end-point event did not occur.
‡
The age listed is the age at randomization rather than the age at the time of initial screening.
§
Data on hemoglobin F at baseline were categorized as not available (NA) if the test was performed before the participant was 3 years of age or if the test was not performed.