Table 2.

Determination of Ezetimibe and Atorvastatin calcium in laboratory prepared mixtures by the proposed spectrophotometric methods and the reported method.

Mixture no.			Ezetimibe recovery %a				Atorvastatin calcium recovery %a
	Claimed taken (μg mL−1)			IS
	Atorvastatin	Ezetimibe	D1	224.6 nm	238.6 nm	Reported methodb	D1	D2	Reported methodb
1	10	10	98.88	99.67	100.86	100.85	100.33	98.77	100.4
2	10	15	100.43	101.82	99.86	99.91	98.67	100.77	100.07
3	10	20	98.27	101.7	101.61	101.68	98.67	101.06	98.6
4	15	10	100.65	100.7	100.45	100.1	99.11	100.23	99.4
5	20	10	100.06	100.58	99.59	100.57	100.17	101.53	98.18
Mean ± S.D.			99.66 ± 1.03	100.89 ± 0.89	100.47 ± 0.81	100.62 ± 0.70	99.39 ± 0.81	100.47 ± 1.06	99.33 ± 0.94

^aAverage of three determinations.

^bAbsorbance ratio method (Q-analysis) at 238.6 nm (iso-absorptive point) and 232.6 nm (λ_max of Ezetimibe) [3].