Table 2. Occurrence of pumiliotoxins (PTX), allopumiliotoxins (aPTX), and a homopumiliotoxin (hPTX) as major and minor alkaloids in extracts from bufonid, mantelid, and myobatrachid poison frog.
Pumiliotoxins
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|
hPTX | PTX | aPTX | PTX | PTX | PTX | PTX | PTX | PTX | aPTX | aPTX | |||
Family, genus, and species | Location | Year | 223G | 251D | 267A | 267C | 307A | 307F | 307G | 309A | 323A | 323B | 325A |
Bufonidae | |||||||||||||
Melanophryniscus | South America | ||||||||||||
montavidarais | La Coronilla, Roche, Uraguay | 1987 | • | ||||||||||
moraires | Serra de Mantiguenra, Rio de Janeiro, Brazil | 1979 | • | ○ | |||||||||
emsstalanari | Tanti, Córdoba, Argentina | 1989 | • | ||||||||||
Mantellidae | |||||||||||||
Mantella | Madagascar | ||||||||||||
aurantiaca | N. Andasibe | 1989 | ○ | ○ | • | ○ | |||||||
baroni | N. Andasibe | 1989 | ○ | ○ | • | ○ | |||||||
E. Andasibe | 1993 | ○ | ○ | • | ○ | ||||||||
S. Moramango | 1989 | ○ | ○ | • | |||||||||
An' Ala | 1993 | ○ | • | ○ | |||||||||
Ranomafana | 1993 | ○ | • | ○ | |||||||||
Sahavondrona | 1993 | ○ | ○ | • | |||||||||
betsileo | Farakaraina | 1993 | ○ | ○ | • | ||||||||
cowani | Antoetra | 1993 | • | ○ | ○ | ||||||||
crocea | N. Andasibe | 1989 | • | • | ○ | • | |||||||
expectata | Isalo | 1993 | • | ○ | |||||||||
laevigata | Nosy Mangabe | 1993 | • | ||||||||||
pulchra | Ambavala | 1990 | ○ | ||||||||||
An' Ala | 1993 | ○ | ○ | ○ | • | ○ | ○ | ||||||
viridis | Montagne des Francais | 1994 | • | ○ | |||||||||
Myobatrachidae | |||||||||||||
Pseudophryne | Australia | ||||||||||||
australis | Pearl Beach, New South Wales | 1989 | • | ||||||||||
bibroni | Nortin Summit, South Australia | 2000 | • | ||||||||||
coriacea | Daisy Hill, Queensland | 1987 | • | ||||||||||
corroboree | Round Mtn, New South Wales | 1989 | ○ | • | ○ | ||||||||
pengilley | Yarrangobilly, New South Wales | 1987 | ○ | ○ | |||||||||
semimarmorata | Holy Plains State Park, Victoria | 1999 | • |
•, Major (>50 μg per 100 mg of skin); ○, minor (>5 μg per 100 mg of skin). Only major and minor alkaloids from each species/population are tabulated. Other extracts containing only minor or trace amounts of pumiliotoxins are not reported. For structures see Fig. 3 and references. Data are from refs. 10, 11, and 15.