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. Author manuscript; available in PMC: 2014 Oct 13.

Published in final edited form as: Toxicol Pathol. 2009 Dec 15;38(1):9–36. doi: 10.1177/0192623309354111

(A) Typical skin lesion from a Tg.AC mouse (squamous papilloma). (B) Skin lesion from a Tg.AC mouse (squamous papilloma). (C) Malignant squamous cell transformation adjacent to a papilloma in a Tg.AC mouse. (D) Odontoma with tooth elements from a Tg.AC mouse. (E) Atypical odontoma from the oral cavity of a Tg.AC mouse. (F) Erythroleukemia in the bone marrow of a Tg.AC mouse. (G) Erythroleukemia in the bone marrow of a Tg.AC mouse (higher magnification). (H) Erythroleukemia in the lung of a Tg.AC mouse. Pulmonary capillaries are highly cellular. (I) Splenic extramedullary hematopoiesis in a Tg.AC mouse. Megakaryocytic, myeloid, and erythroid cells are present within the hypercellular splenic parenchyma.

(A) Typical skin lesion from a Tg.AC mouse (squamous papilloma). (B) Skin lesion from a Tg.AC mouse (squamous papilloma). (C) Malignant squamous cell transformation adjacent to a papilloma in a Tg.AC mouse. (D) Odontoma with tooth elements from a Tg.AC mouse. (E) Atypical odontoma from the oral cavity of a Tg.AC mouse. (F) Erythroleukemia in the bone marrow of a Tg.AC mouse. (G) Erythroleukemia in the bone marrow of a Tg.AC mouse (higher magnification). (H) Erythroleukemia in the lung of a Tg.AC mouse. Pulmonary capillaries are highly cellular. (I) Splenic extramedullary hematopoiesis in a Tg.AC mouse. Megakaryocytic, myeloid, and erythroid cells are present within the hypercellular splenic parenchyma.