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. Author manuscript; available in PMC: 2014 Oct 13.
Published in final edited form as: Toxicol Pathol. 2009 Dec 15;38(1):9–36. doi: 10.1177/0192623309354111

Figure 9.

Figure 9

(A) Focal epithelial proliferation in the forestomach of a two-year-old female Wistar rat. Note elevation from the adjacent unaffected epithelium mimicking a “sessile papilloma.” (B) Higher magnification showing prominent development of rete pegs, built up mainly by basal and prickle cells. (C) Focal basal cell hyperplasia in the forestomach of a two-year-old female Wistar rat. Note proliferation of basal cell layers and orderly structure of stratum granulosum and corneum. (D) Higher magnification of (C) showing proliferation of basal cells forming tightly packed papillary projections. (E) Proliferation of basal cells in the gastric glandular mucosa of a two-year-old male Wistar rat. Note proximity to the limiting ridge. (F) Higher magnification of (E) demonstrating the basal cell character of this epithelial proliferation.