Table 1. Pearson correlation analyses of androgen levels with clinical and biochemical parameters in PCOS women (n = 706).
Free testosterone | Testosterone | Androstenedione | Androstenedione/free testosterone-ratio | |||||
Endocrine characteristics | ||||||||
Testosterone | 0.735 | <0.001 | 1 | 0.553 | <0.001 | −0.175 | <0.001 | |
Androstenedione | 0.459 | <0.001 | 0.553 | <0.001 | 1 | 0.444 | <0.001 | |
Androstenedione/free testosterone-ratio | −0.518 | <0.001 | −0.234 | <0.001 | 0.444 | <0.001 | 1 | |
SHBG | −0.649 | <0.001 | −0.042 | 0.298 | −0.100 | 0.014 | 0.567 | <0.001 |
FAI | 0.967 | <0.001 | 0.574 | <0.001 | 0.387 | <0.001 | −0.560 | <0.001 |
DHEAS | 0.286 | <0.001 | 0.222 | <0.001 | 0.350 | <0.001 | 0.094 | 0.042 |
Clinical characteristics | ||||||||
Age | −0.138 | 0.002 | −0.136 | <0.001 | −0.204 | <0.001 | −0.051 | 0.265 |
BMI | 0.390 | <0.001 | 0.085 | 0.037 | −0.027 | 0.510 | −0.431 | <0.001 |
Waist circumference | 0.342 | <0.001 | −0.008 | 0.862 | −0.096 | 0.031 | −0.447 | <0.001 |
Waist-to-hip ratio | 0.245 | <0.001 | 0.085 | 0.037 | −0.027 | 0.510 | −0.386 | <0.001 |
Total body fat | 0.196 | 0.006 | 0.035 | 0.622 | 0.014 | 0.854 | −0.221 | 0.003 |
Fat mass | 0.368 | <0.001 | 0.112 | 0.119 | 0.039 | 0.539 | −0.404 | <0.001 |
Subcutaneous adipose tissue mass | 0.329 | <0.001 | 0.097 | 0.174 | 0.030 | 0.679 | −0.370 | <0.001 |
Visceral adipose tissue mass | 0.321 | <0.001 | 0.088 | 0.220 | 0.042 | 0.568 | −0.329 | <0.001 |
Systolic BP | 0.218 | <0.001 | 0.112 | 0.013 | 0.065 | 0.147 | −0.171 | 0.001 |
Diastolic BP | 0.190 | <0.001 | 0.133 | 0.003 | 0.075 | 0.093 | −0.143 | 0.004 |
Ferriman-Gallwey score | 0.213 | <0.001 | 0.044 | 0.301 | −0.011 | 0.794 | −0.191 | <0.001 |
Metabolic characteristics | ||||||||
Fasting glucose | 0.148 | 0.001 | 0.094 | 0.021 | 0.090 | 0.029 | −0.099 | 0.032 |
2 h glucose | 0.179 | <0.001 | −0.009 | 0.838 | 0.018 | 0.667 | −0.196 | <0.001 |
AUCgluc | 0.135 | 0.015 | 0.019 | 0.688 | 0.033 | 0.491 | −0.148 | 0.007 |
HbA1c | 0.219 | <0.001 | 0.050 | 0.237 | 0.045 | 0.291 | −0.174 | <0.001 |
Fasting insulin | 0.340 | <0.001 | 0.088 | 0.035 | 0.071 | 0.087 | −0.314 | <0.001 |
Insulin 2 h | 0.303 | <0.001 | 0.101 | 0.017 | 0.093 | 0.028 | −0.314 | <0.001 |
AUCins | 0.283 | <0.001 | 0.088 | 0.074 | 0.020 | 0.688 | −0.288 | <0.001 |
HOMA | 0.351 | <0.001 | 0.100 | 0.017 | 0.078 | 0.062 | −0.314 | <0.001 |
QUICKI | −0.340 | <0.001 | −0.093 | 0.027 | −0.078 | 0.062 | 0.303 | <0.001 |
Matsuda-index | −0.309 | <0.001 | −0.068 | 0.171 | −0.067 | 0.183 | 0.295 | <0.001 |
Oral disposition index | −0.055 | 0.336 | 0.039 | 0.435 | −0.075 | 0.128 | 0.001 | 0.991 |
Triglycerides | 0.223 | <0.001 | 0.100 | 0.014 | −0.013 | 0.746 | −0.269 | <0.001 |
Total cholesterol | 0.034 | 0.461 | 0.113 | 0.006 | 0.021 | 0.608 | −0.005 | 0.919 |
LDL cholesterol | 0.094 | 0.064 | −0.025 | 0.572 | −0.042 | 0.343 | −0.132 | 0.008 |
HDL cholesterol | −0.235 | <0.001 | 0.043 | 0.295 | 0.076 | 0.063 | 0.344 | <0.001 |
Total cholesterol/HDL cholesterol-ratio | 0.212 | <0.001 | 0.010 | 0.812 | −0.081 | 0.049 | −0.322 | <0.001 |
PCOS polycystic ovary syndrome, SHBG sex-hormone binding globulin, FAI free androgen index, DHEAS dehydroepiandrosterone sulphate, BMI body mass index, BP blood pressure, AUC area under the curve, HOMA-IR homeostatic model assessment insulin resistance, QUICKI quantitative insulin sensitivity check index, LDL low density lipoprotein, HDL high density lipoprotein.