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. 2014 Oct 13;9(10):e108263. doi: 10.1371/journal.pone.0108263

Table 1. Pearson correlation analyses of androgen levels with clinical and biochemical parameters in PCOS women (n = 706).

Free testosterone Testosterone Androstenedione Androstenedione/free testosterone-ratio
Endocrine characteristics
Testosterone 0.735 <0.001 1 0.553 <0.001 −0.175 <0.001
Androstenedione 0.459 <0.001 0.553 <0.001 1 0.444 <0.001
Androstenedione/free testosterone-ratio −0.518 <0.001 −0.234 <0.001 0.444 <0.001 1
SHBG −0.649 <0.001 −0.042 0.298 −0.100 0.014 0.567 <0.001
FAI 0.967 <0.001 0.574 <0.001 0.387 <0.001 −0.560 <0.001
DHEAS 0.286 <0.001 0.222 <0.001 0.350 <0.001 0.094 0.042
Clinical characteristics
Age −0.138 0.002 −0.136 <0.001 −0.204 <0.001 −0.051 0.265
BMI 0.390 <0.001 0.085 0.037 −0.027 0.510 −0.431 <0.001
Waist circumference 0.342 <0.001 −0.008 0.862 −0.096 0.031 −0.447 <0.001
Waist-to-hip ratio 0.245 <0.001 0.085 0.037 −0.027 0.510 −0.386 <0.001
Total body fat 0.196 0.006 0.035 0.622 0.014 0.854 −0.221 0.003
Fat mass 0.368 <0.001 0.112 0.119 0.039 0.539 −0.404 <0.001
Subcutaneous adipose tissue mass 0.329 <0.001 0.097 0.174 0.030 0.679 −0.370 <0.001
Visceral adipose tissue mass 0.321 <0.001 0.088 0.220 0.042 0.568 −0.329 <0.001
Systolic BP 0.218 <0.001 0.112 0.013 0.065 0.147 −0.171 0.001
Diastolic BP 0.190 <0.001 0.133 0.003 0.075 0.093 −0.143 0.004
Ferriman-Gallwey score 0.213 <0.001 0.044 0.301 −0.011 0.794 −0.191 <0.001
Metabolic characteristics
Fasting glucose 0.148 0.001 0.094 0.021 0.090 0.029 −0.099 0.032
2 h glucose 0.179 <0.001 −0.009 0.838 0.018 0.667 −0.196 <0.001
AUCgluc 0.135 0.015 0.019 0.688 0.033 0.491 −0.148 0.007
HbA1c 0.219 <0.001 0.050 0.237 0.045 0.291 −0.174 <0.001
Fasting insulin 0.340 <0.001 0.088 0.035 0.071 0.087 −0.314 <0.001
Insulin 2 h 0.303 <0.001 0.101 0.017 0.093 0.028 −0.314 <0.001
AUCins 0.283 <0.001 0.088 0.074 0.020 0.688 −0.288 <0.001
HOMA 0.351 <0.001 0.100 0.017 0.078 0.062 −0.314 <0.001
QUICKI −0.340 <0.001 −0.093 0.027 −0.078 0.062 0.303 <0.001
Matsuda-index −0.309 <0.001 −0.068 0.171 −0.067 0.183 0.295 <0.001
Oral disposition index −0.055 0.336 0.039 0.435 −0.075 0.128 0.001 0.991
Triglycerides 0.223 <0.001 0.100 0.014 −0.013 0.746 −0.269 <0.001
Total cholesterol 0.034 0.461 0.113 0.006 0.021 0.608 −0.005 0.919
LDL cholesterol 0.094 0.064 −0.025 0.572 −0.042 0.343 −0.132 0.008
HDL cholesterol −0.235 <0.001 0.043 0.295 0.076 0.063 0.344 <0.001
Total cholesterol/HDL cholesterol-ratio 0.212 <0.001 0.010 0.812 −0.081 0.049 −0.322 <0.001

PCOS polycystic ovary syndrome, SHBG sex-hormone binding globulin, FAI free androgen index, DHEAS dehydroepiandrosterone sulphate, BMI body mass index, BP blood pressure, AUC area under the curve, HOMA-IR homeostatic model assessment insulin resistance, QUICKI quantitative insulin sensitivity check index, LDL low density lipoprotein, HDL high density lipoprotein.