Table 4. Associations between coronary sinus miR levels and surrogate markers of cardiovascular disease.
Marker | miR-17 | miR-21 | miR-34 | miR-92 | miR-126 | miR-133 | miR-145 | miR-155 | miR-181 | miR-208 | miR-221 | miR-222 | |
Hemoglobin | 0.0677 | −0.0368 | 0.3365* | −0.1227 | 0.4724* | −0.0348 | −0.1850 | −0.1890 | 0.3315 | 0.2128 | 0.2536 | 0.1602 | |
Leukocytes | 0.0816 | −0.1025 | −0.1758 | 0.1375 | 0.2642 | 0.2073 | 0.2831 | 0.2733 | −0.1854 | −0.0499 | −0.0165 | 0.0684 | |
Monocytes | −0.0161 | −0.1015 | 0.1631 | −0.0413 | 0.2811 | 0.1336 | 0.4713* | 0.2803 | 0.2680 | −0.1607 | 0.1521 | 0.0479 | |
Lymphocytes | 0.1357 | −0.1751 | 0.3022 | 0.0822 | 0.0159 | 0.1901 | 0.2319 | 0.1018 | 0.2826 | 0.0161 | 0.2680 | 0.0745 | |
Platelets | −0.2285 | −0.0986 | 0.0920 | −0.3743* | −0.0642 | 0.2422 | 0.3232 | 0.0904 | 0.1349 | 0.0259 | 0.1440 | 0.1812 | |
Total Cholesterol | −0.0598 | 0.0532 | 0.0455 | 0.0300 | −0.0239 | 0.1806 | −0.0209 | −0.0086 | −0.0553 | 0.2603 | 0.0023 | −0.0136 | |
LDL-Cholesterol | −0.0712 | 0.0198 | −0.0552 | −0.0071 | 0.0630 | 0.2030 | 0.0257 | 0.1013 | −0.1141 | 0.2471 | −0.0464 | −0.0157 | |
HDL-Cholesterol | −0.2169 | 0.1301 | 0.1685 | −0.0701 | −0.1420 | −0.2494 | −0.1602 | −0.2434 | 0.1732 | 0.0352 | 0.2511 | 0.2300 | |
Triglycerides | 0.1909 | −0.0065 | 0.1381 | −0.0816 | 0.0983 | 0.3272 | −0.1362 | 0.0813 | −0.1870 | 0.1150 | −0.1989 | −0.1705 | |
Glucose | −0.0353 | 0.0052 | −0.3173 | 0.1435 | 0.2346 | 0.3712* | 0.0260 | 0.1365 | −0.3721* | −0.1724 | −0.1853 | −0.2754 | |
HbA1c | −0.1202 | −0.3273 | 0.0332 | −0.1576 | 0.0122 | 0.0404 | 0.2455 | 0.1549 | 0.0310 | −0.0434 | 0.0483 | −0.0071 | |
Insulin | −0.0032 | 0.1207 | −0.2042 | 0.1294 | −0.0506 | 0.1030 | −0.0371 | −0.0883 | −0.3219 | −0.1858 | 0.0053 | 0.1492 | |
BNP | 0.1442 | 0.0051 | 0.0647 | 0.2027 | 0.1747 | 0.0616 | 0.0941 | 0.0519 | −0.0952 | −0.0277 | −0.0774 | −0.1399 | |
hs-CRP | −0.1655 | −0.0192 | −0.1665 | 0.0119 | 0.0060 | −0.0499 | 0.1987 | 0.0485 | −0.0896 | −0.3033 | 0.0478 | 0.2048 | |
Homycystein | −0.0817 | 0.1460 | 0.0064 | −0.2101 | −0.0618 | −0.1340 | 0.1215 | −0.1450 | 0.1662 | −0.0978 | 0.1951 | 0.0630 | |
LPA-2 | −0.0724 | −0.4202* | 0.1536 | −0.2022 | −0.0401 | −0.1479 | −0.1124 | −0.0020 | −0.0354 | −0.2309* | −0.0538 | −0.2161 | |
Vitamin B12 | 0.1683 | −0.0283 | 0.3259 | −0.0721 | −0.2911 | −0.1933 | −0.3486* | −0.1650 | 0.0784 | −0.1978 | −0.2482 | −0.1628 |
Multivariable analysis of miR levels and certain surrogate markers of CHD. Spearman's rank correlation coefficient are given with asterisks indicating significant positive or negative correlations set by a p-value <0.05 (*).