Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Oct 13;9(10):e109623. doi: 10.1371/journal.pone.0109623

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Jayachandran et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

PMC Copyright notice

A & B. Optimal 6-TGN concentration and optimal 6-MP regimen respectively, for a patient with low TPMT enzyme activity. C & D. Optimal profiles for a patient with high TPMT enzyme activity. Patient with low TPMT activity required significantly lower dose compared to the standard treatment and vice versa. Dashed line shows the therapeutic target level.