Fig. 4.
Exploration of empty holeboard facilitates LTP. (a) Weak HFT (100 pulses at 100 Hz) given at the time point indicated by the arrow induces short-term potentiation. Weak HFT given at the beginning of 15 min of empty holeboard exploration (white box) facilitates short-term potentiation into LTP. (b) Analog traces (Upper) represent potentials recorded before HFT, 20 min after HFT, and 24 h after HFT, in an HFT experiment. (Lower) fEPSPs observed before HFT, 5 min after holeboard removal (i.e., 20 min after HFT), and 24 h after HFT. Vertical scale bar corresponds to 0.5 mV, and horizontal bar corresponds to 5 ms.