Table 3.
Summary of carotid plaque variables from all subjects (N=214) and from those with lipid-rich necrotic core present (N=112).
| All subjects | Value | ||
|---|---|---|---|
| AHA lesion type (any) | |||
| III | 124 (58%) | ||
| IV-V | 110 (51%) | ||
| VI | 23 (11%) | ||
| VII | 76 (36%) | ||
|
| |||
| AHA lesion type (most severe*) | |||
| I-II (no detectable plaque) | 49 (23%) | ||
| III | 21 (10%) | ||
| IV-V | 91 (43%) | ||
| VI | 23 (11%) | ||
| VII | 30 (14%) | ||
|
| |||
| Carotid Atherosclerosis Score (CAS) | |||
| 1 (low risk) | 75 (35%) | ||
| 2 (medium-low risk) | 91 (43%) | ||
| 3 (medium-high risk) | 22 (10%) | ||
| 4 (high risk) | 26 (12%) | ||
|
| |||
| Presence of lipid-rich necrotic core | 112 (52%) | ||
| Presence of calcification | 103 (48%) | ||
| Presence of loose matrix | 21 (10%) | ||
| Presence of intraplaque hemorrhage | 18 (8.4%) | ||
| Presence of surface defect | 17 (7.9%) | ||
| Presence of mural thrombus | 1 (0.5%) | ||
|
| |||
| Wall volume (mm3) | 788 ± 232 | 741 | (387 - 1965) |
| % wall volume (%) | 42 ± 7 | 41 | (27 - 69) |
| Mean wall thickness (mm) | 1.1 ± 0.2 | 1.1 | (0.8 - 2.4) |
| Max wall thickness (mm) | 2.7 ± 1.4 | 2.5 | (0.9 - 8.0) |
|
| |||
| Subjects with lipid-rich necrotic core | |||
|
| |||
| Lipid-rich necrotic core volume (mm3) | 76 ± 126 | 31 | (4 - 735) |
| % wall volume (%) | 45 ± 7 | 44 | (29 - 69) |
| % lipid-rich necrotic core volume (%)† | 14 ± 10 | 10 | (3 - 51) |
| % calcification volume (%)† | 1.6 ± 2.6 | 0 | (0 - 12) |
| % loose matrix volume (%)† | 0.4 ± 1.3 | 0 | (0 - 9.0) |
| % fibrous tissue volume (%)† | 84 ± 11 | 88 | (43 - 97) |
Continuous data are presented as mean ± standard, median and (range);
Categorical data are presented as n (%);
*
AHA lesion types in order of increasing severity: I-II, III, VII, IV-V, VI;
†
As a percentage of the wall volume from locations with lipid-rich necrotic core present.