Table 1.
Baseline clinical characteristic of patients and controls
| Control group (n = 75) | CAD group (n = 75) | CTO group (n = 75) | p | |
|---|---|---|---|---|
| Age, years | 58 ± 11 | 63 ± 10 | 61 ± 8 | 0.01 |
| Male, n (%) | 34 (45.3) | 49 (65.3) | 66 (88) | <0.001 |
| Diabetes mellitus, n (%) | 12 (16) | 30 (40) | 26 (34.7) | 0.004 |
| Hypertension, n(%) | 50 (66.7) | 55 (73.3) | 49 (65.3) | 0.52 |
| Hyperlipidemia, n (%) | 19 (25.3) | 44 (58.7) | 52 (69.3) | <0.001 |
| Family history of CAD, n (%) | 2 (2.7) | 4 (5.3) | 29 (38.7) | <0.001 |
| Smoking, n (%) | 25 (33.3) | 33 (44.4) | 39 (52) | 0.06 |
| Ejection fraction, % | 57.9 ± 7.4 | 55.1 ± 10 | 51.3 ± 9.1 | <0.001 |
| Hemoglobin, g/dL | 14.2 ± 1.6 | 13.8 ± 1.6 | 13.7 ± 1.7 | 0.16 |
| Platelet, 103/ml | 233 ± 61 | 251 ± 75 | 233 ± 68 | 0.17 |
| WBC, 103/ml | 7.40 ± 1.84 | 7.93 ± 1.96 | 8.63 ± 1.94 | 0.001 |
| Neutrophil, 103/ml | 4.16 ± 1.27 | 4.78 ± 1.36 | 5.62 ± 1.49 | <0.001 |
| Lymphocyte,103/ml | 2.46 ± 0.76 | 2.33 ± 0.67 | 2.11 ± 0.72 | 0.01 |
| NLR | 1.79 ± 0.57 | 2.13 ± 0.64 | 2.95 ± 1.29 | <0.001 |
| Gensini score | 1.5 (0-13) | 26 (2-128) | 64 (33.5-158) | <0.001 |
| SYNTAX score | 10.3 ± 6.8 | 19.2 ± 7.6 | <0.001 |
CAD, coronary artery disease; CTO, coronary total occlusion; NLR, neutrophil-to-lymphocyte ratio; WBC, white blood cell.
Significant p values are bold.