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Chronic mechanical allodynia develops normally in α9-nAChR KO mice. Inflammatory (A and C) and neuropathic (B and D) pain models produce chronic mechanical allodynia in both WT and KO animals. Response frequency to von Frey stimulation increases following injury (A and B). The ratio of weight-bearing on injured versus uninjured hind-paws decreases post injury (B and C).
