Table 1 . Perioperative characteristics of the patients .
|
Caproamin Fides
(n=100) |
TXA
(n=100) |
Control
(n=100) |
P | |
| Male | 75 (75) | 70 (70) | 65 (65) | 0.30 |
| Age | 59±10 | 58±9 | 59±10 | 0.83 |
| BSA (kg/m 2 ) | 1.88±0.14 | 1.77±0.14 | 1.78±0.18 | <0.001* |
| Hemoglobin (g/dL) | 14.32±1.71 | 13.97±2.02 | 14.21±1.54 | 0.65 |
| Diabetes | 42 (42) | 39 (39) | 51 (51) | 0.20 |
| HTN | 40 (40) | 40 (40) | 47 (47) | 0.51 |
| History of MI | 30 (30) | 29 (29) | 40 (40) | 0.18 |
| Renal failure | 1 (1) | 7 (7) | 13 (13) | 0.004* |
| Duration of taking clopidogrel (months) | 48 | 44 | 36 | 0.21 |
| Frequency of surgery | 0.44 | |||
| First surgery | 98 (98) | 99 (99) | 96 (96) | |
| Redo surgery | 2 (2) | 1 (1) | 4 (4) | |
| Graft no. | 3.29±0.90 | 3.50±0.75 | 3.37±0.77 | 0.76 |
| AOX time (min) | 41±19 | 46±19 | 44±21 | 0.20 |
| CPB time (min) | 76±28 | 86±28 | 90±40 | 0.01* |
| Operation time (min) | 260±50 | 241±54 | 241±63 | 0.02* |
Data are shown as number (percentage) and mean±standard deviation.
AOX= aortic cross-clamping; BSA= body surface area; CPB= cardiopulmonary bypass; HTN= hypertension; MI= myocardial infarction.
*Statistically significant.