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. 2014 Oct 2;12:45. doi: 10.1186/1546-0096-12-45

Figure 5.

Figure 5

Key functions of the tumor necrosis factor (TNF)-α cytokine in tuberculosis. (A) TNF-α recruits neutrophils, macrophages and T-lymphocytes to the infection site; (B) The cytokine maintains granuloma formation in tuberculosis; (C) The autocrinal TNF-α is also produced and induces apoptosis of TB-infected cells.