Table 2.
Generation of clinical grade products
| Number of plates | Number positive wells | Least % positive sorted | Largest % positive (all sorted) | Mean % positive | Number of wells used for expansion to final product | Total cells after mini-REP (×10^6) | Bag REP vs. GREX REP | Cells started for large volume expansion (×10^6) | Final cell number (×10^9) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Patient 1 | 3 | 3 | 0.62% | 8.05% | 3.39% | 3 | 230 | Bag | 33 | 57.9 |
| Patient 2 | 1 | 5 | 0.57% | 1.90% | 1.00% | 5 | 73 | GREX | 68 | 44.2 |
| Patient 3 | 1 | 7 | 0.01% | 5.23% | 1.23% | 7 | 224 | GREX | 25 | 26.4 |
| Patient 4 | 2 | 6 | 0.11% | 3.68% | 1.03% | 4 | 157 | GREX | 19 | 20.7 |
| Patient 5 | 2 | 3 | 0.07% | 1.55% | 0.57% | 3 | 331 | GREX | 32 | |
| Patient 6 | 2 | 5 | 0.11% | 7.24% | 2.80% | 1 | 169 | Bag | 18 | 24.6 |
| Mean | 1.8 | 4.8 | 0.2% | 4.6% | 1.7% | 3.8 | 197.3 | 32.4 | 34.8 |