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. 2014 Nov 1;37(11):1825–1832. doi: 10.5665/sleep.4180

Figure 3.

Figure 3

Serum VEGF activates endothelial repair in vitro. (A) Pictures in phase contrast microscopy (x10 magnification) showing examples of wounds after 7.5 h of healing by endothelial cells, in presence of pooled Healthy Controls serum or pooled OSA patients serum in EBM medium. Bar = 50 μm. (B) Serum from OSA patients diminish endothelial healing compared to healthy controls serum, and anti-VEGF blocking antibody (0.5 μg/mL) but not control antibody added in OSA patient serum inhibits endothelial healing. Two-Way ANOVA, * P < 0.001 compared to control, # P < 0.05 compared to OSA without antibody or control antibody. N = at least 6 independent experiments, error bars represent SEM.