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. 2014 Oct 14;4:6609. doi: 10.1038/srep06609

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A) The average SPR sensorgram of each clone and the corresponding two-constant (H6 and C5) or one-constant (E8 and C11) fitting. B) The resistance index (RI) map of each clone, demonstrating the potency of individual cell being resistant to Herceptin treatment. C) SPR sensorgrams of two individual cells are shown to demonstrate the cell-to-cell variation when interacts with Herceptin. Scale bars, 100 μm.