Figure 1.

Influence of 28 days of bed rest and 14 days active recovery on plasma IGF-1, Adiponectin, HDL-cholesterol, total Cholesterol and Triglyceride levels. Plasma levels of a) IGF-1, b) Total adiponectin, c) HDL-cholesterol, d) Total-cholesterol, e) Triglycerides, f) HDL:total-cholesterol ratio. Values are reported as mean ± SEM except median ± IQR (Total adiponectin, log transformed values). Participants were randomized into amino acid supplement (EAA) group or resistance training with amino acid supplement (RT) group. Open bars: baseline values; grey bars: values after 28 days of BR; filled bars: values after 14 days of active recovery. Repeated measures analyses using General Linear Models (GLM) were carried out to assess the interaction between time [baseline (or pre-bed rest), end of bedrest, and recovery] and group [amino acids vs amino acids plus exercise] on each of the dependent variable studied. * p < 0.01 for time effect, ** p < 0.05 for time-by-group interaction.