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. 2014 Jul 21;5(16):6701–6715. doi: 10.18632/oncotarget.2239

Figure 1. DPT is down-regulated and closely related to patient prognosis in hepatocellular carcinoma (HCC).

Figure 1

(A) Relative mRNA expression of DPT, as determined by qPCR, in 36 pairs of HCC tissues and their paracancerous liver (PCL) tissues. Values are means ± SEM (*** P < 0.001). (B) Western blotting analysis of DPT expression in 14 pairs of HCC and PCL. P represents paracancerous liver tissues and H represents HCC tissues. The densitometric analysis of the results was shown below. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was included as a loading control. Values are means ± SEM (*** P < 0.001). (C) Immunohistochemical staining of DPT in HCC and PCL (Original magnification: a, b, e and f, 200x; c, d, g and h, 400x). Scale bars, 10μm. (D) The expression of DPT was down-regulated in 73.23% of the HCC patients. n = 168. (E) Kaplan-Meier analysis of overall survival for the expression of DPT (P = 0.023). (F) Kaplan-Meier analysis of relapse-free survival for the expression of DPT (P = 0.008).