Table 1. Clinicopathological correlation of DPT expression in 202 HCC patients using Pearson's x2 test.
| Variable | DPT (n) | |||
|---|---|---|---|---|
| High, n (%) | Low, n (%) | P | ||
| Age | ≤50 years | 23 (11.39) | 81 (40.10) | 0.184 |
| >50 years | 42 (20.79) | 56 (27.72) | ||
| Gender | Female | 8 (3.96) | 20 (9.90) | 0.660 |
| Male | 57 (28.22) | 117 (57.92) | ||
| Liver Cirrhosis | Yes | 56 (27.72) | 121 (59.90) | 0.662 |
| No | 9 (4.46) | 16 (7.92) | ||
| Local | Yes | 9 (4.50) | 13 (6.50) | 0.372 |
| No | 56 (28.00) | 122 (61.00) | ||
| Tumor multiplicity | Single | 56 (27.72) | 112 (55.45) | 0.435 |
| Multiple | 9 (4.45) | 25 (12.38) | ||
| Serum AFP | ≤20ng/ml | 30 (15.00) | 39 (19.50) | 0.016 |
| >20ng/ml | 35 (17.50) | 96 (48.00) | ||
| Tumor satellite | Yes | 7 (3.48) | 25(12.44) | 0.168 |
| No | 58 (28.86) | 111(55.22) | ||
| Tumor encapsulation | None | 27 (13.43) | 82 (40.80) | 0.013 |
| Complete | 38 (18.90) | 54 (26.87) | ||
| Thromb | Yes | 6 (2.97) | 38 (18.81) | 0.003 |
| No | 59 (29.21) | 99 (49.01) | ||
| Tumor differentiation | I | 1 (0.50) | 2 (0.99) | 0.017 |
| II | 32 (15.92) | 40 (19.90) | ||
| III | 32 (15.92) | 94 (46.77) | ||
| Vascular invasion | Yes | 10 (4.95) | 47 (23.27) | 0.005 |
| No | 55 (27.23) | 90 (44.55) | ||
| Tumor size | ≤5 cm | 37 (18.32) | 65 (32.18) | 0.208 |
| >5 cm | 28 (13.86) | 72 (35.64) | ||
| TNM stage | I | 46 (22.77) | 73 (36.14) | 0.047 |
| II | 8 (3.96) | 15 (7.43) | ||
| III | 11 (5.44) | 49 (24.26) | ||
Tumor differentiation: Tumors were divided into three groups according to the Edmondson–Steiner classification. Grade I: well differentiated tumors. Grade II: moderately differentiated tumors. Grade III: poorly differentiated tumors.
TNM stage: HCC tumors were classified according to the staging system by the International Union against Cancer (UICC) as follows: Stage I, encapsulated and without evidence of liver or vascular invasion; Stage II, unencapsulated or capsulated and with liver invasion but without vascular invasion; Stage III, invasion of small vessels in the tumor capsule or focal invasion of portal vein branches close to the tumor or invasion of the portal vein in distal the liver, branches of the major portal vein, and the common bile duct or perforation into visceral peritoneum.