Figure 5. Histiocytic sarcomas and soft tissue sarcomas from mice with Ptprd and Cdkn2a deletion.
(A) Representative images of histiocytic sarcoma. Left, H&E staining of Ptprd+/+Cdkn2a−/− liver histiocytic sarcoma. Left, scale bar = 200μm; Middle, higher magnification of left image with scale bar = 50μm; Right, Mac-2 staining of Ptprd+/+Cdkn2a−/− liver histiocytic sarcoma with scale bar = 200μm. (B) Representative images of soft tissue sarcoma. Left, H&E staining of Ptprd+/−Cdkn2a−/− fibrosarcoma with scale bar = 500μm; Right, higher magnification of left image with scale bar = 100μm. (C) Representative images of Ptprd+/+Cdkn2a−/−, Ptprd+/−Cdkn2a−/−, and Ptprd−/−Cdkn2a−/− histiocytic sarcomas stained with Ki67, TUNEL, CD34, and p-Stat3. Scale bars = 50μm.